Obesity Genomics & Genetics

Childhood obesity linked to chromosome 6q22.31-q23.2 in French families

Published in Obesity and Diabetes Week, April 26th, 2004

A genome-wide scan for childhood obesity-associated traits in French families shows significant linkage on chromosome 6q22.31-q23.2.

According to recent research from France, "We conducted a genome-wide search for childhood obesity-associated traits, including BMI {{>=}}95th percentile (PCT95), 97th percentile (PCT97), and 99th percentile (PCT99) as well as age of adiposity rebound (AAR), which corresponds to the beginning of the second rise in childhood adiposity. A set of 431 microsatellite markers was genotyped in 506 subjects from 115 multiplex French Caucasian families, with at least one child with a BMI {{>=}}95th percentile. Among these 115 pedigrees, 97...

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Source: Obesity and Diabetes Week (2004-04-26)

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