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Animal Model

Model for study of multiple wounds in the diabetic mouse validated

Published in Obesity and Diabetes Week, May 10th, 2004

Scientists have validated a model for the study of multiple wounds in the diabetic mouse (db/db).

"The genetically diabetic db/db mouse exhibits symptoms that resemble human type 2 diabetes mellitus, demonstrates delayed wound healing, and has been used extensively as a model to study the role of therapeutic topical reagents in wound healing. The purpose of the authors' study was to validate an excisional wound model using a 6-mm biopsy punch to create four full-thickness dorsal wounds on a single db/db mouse," scientists in the United States report.

"Factors considered in developing the db/db wound model include reproducibility of size and shape of...

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