Bone Mineral Density

Inverse relation found between leptin and BMD in hip-fractured women

Published in Obesity and Diabetes Week, May 17th, 2004

An inverse association exists between leptin and bone mineral density (BMD) in hip-fractured women.

According to recent research published in the Journal of Endocrinological Investigation, "Fat body mass (FBM) is a strong predictor of both bone mineral density (BMD) and risk of hip fracture, but the mechanisms responsible are not completely understood. We addressed whether leptin is the link between FBM and BMD in hip-fractured women. Sixty-two of 74 women with hip fractures were evaluated.

"Serum leptin was measured by radioimmunoassay, 23.4±9.1 days (mean±SD) after fracture occurrence," said M. Di Monaco and colleagues at the...

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Source: Obesity and Diabetes Week (2004-05-17)

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