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Obesity and Diabetes

Adiponectin does not rise upon weight loss in insulin-resistant women

Published in Obesity and Diabetes Week, May 24th, 2004

Plasma adiponectin concentrations do not increase in association with moderate weight loss in insulin-resistant, obese women.

"Plasma adiponectin concentrations were measured before and after moderate weight loss in 20 obese women, divided at baseline into insulin-resistant (IR) and insulin-sensitive (IS) subgroups on the basis of their steady-state plasma glucose (SSPG) concentration at the end of a 180-minute infusion of octreotide, glucose, and insulin. The groups were similar in age and body weight and lost comparable amounts of weight (8 to 9 kg) during the weight loss period," scientists writing in the journal Metabolism - Clinical and Experimental...

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