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Diabetes Therapy
Puerarin mediates beta-endorphin to reduce glucose in diabetic rats
May 31st, 2004
The isoflavone puerarin mediates beta-endorphin to lower plasma glucose in diabetic rats. According to recent research from Taiwan, "We investigate the mechanisms of plasma glucose lowering action of puerarin in streptozotocin-induced diabetic rats (STZ-diabetic rats). Puerarin at the effective dosage to lower higher plasma glucose increased plasma beta-endorphin-like immunoreactivity (BER) in STZ-diabetic rats. Both effects of puerarin were abolished by the pretreatment with prazosin. "Also, puerarin enhanced BER release from isolated rat adrenal medulla in a concentration-dependent manner that can be abolished by prazosin," reported Wang-Chuan Chen...
Source: Obesity & Diabetes Week (2004-05-31)
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