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Obesity & Diabetes Week

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Diabetic Nephropathy



Evidence of apoptosis in human diabetic kidney found



May 31st, 2004

Scientists have found evidence of apoptosis in the human diabetic kidney.

According to published research from Canada, "Diabetic nephropathy is characterized by an early period of renal growth with glomerular and tubular cell hypertrophy, but this is followed by progressive glomerulosclerosis and tubulointerstitial fibrosis, associated with loss of renal tissue. We studied whether apoptotic cell death occurs in human diabetic nephropathy. Percutaneous renal biopsy samples were obtained from five patients with diabetic nephropathy who were receiving insulin and/or angiotensin-converting enzyme inhibitor therapy.

"Apoptosis was determined by the...


Source: Obesity & Diabetes Week (2004-05-31)

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