Obesity & Diabetes Week
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Diabetic Neuropathy
Apoptosis of vasopressinergic hypothalamic neurons occurs in diabetes
May 31st, 2004
Apoptosis of vasopressinergic hypothalamic neurons occurs in chronic diabetes. "The hyperosmolality associated with diabetes mellitus triggers an increase in neuronal activity and vasopressin production within magnocellular neurosecretory cells (MNCs) of the hypothalamic supraoptic nucleus (SON). In this study, we examined the effect of chronic diabetes on the function and survival of these neurons. After 6 months, but not 6 weeks, of streptozotocin (STZ)-induced diabetes, we observed an increase in the appearance of small hyperchromatic neurons and a decrease in SON neuronal density," researchers in the United States report. "A subpopulation of...
Source: Obesity & Diabetes Week (2004-05-31)
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