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Endocrinology

Stomach can be considered an endocrine organ

Published in Obesity and Diabetes Week, May 31st, 2004

The relations among ghrelin, appetite, and gastric motility indicate the emerging role of the stomach as an endocrine organ.

According to recent research published in the FASEB Journal, "Recent progress in the field of energy homeostasis was triggered by the discovery of adipocyte hormone leptin and revealed a complex regulatory neuroendocrine network. A late addition is the novel stomach hormone ghrelin, which is an endogenous agonist at the growth hormone secretagogne receptor and is the motilin-related family of regulatory peptides. In addition to its ability to stimulate GH secretion and gastric motility, ghrelin stimulates appetite and induces a positive...

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