Obesity & Diabetes Week
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Exercise
Aerobic exercise may attenuate age-related decline in protein synthesis
May 31st, 2004
Aerobic exercise may attenuate the age-related decline in protein synthesis due to increases in mammalian target of rapamycin (mTOR) and protein kinase B (PKB). "The protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway is thought to play a critical role in the regulation of protein synthesis and skeletal muscle mass. The purpose of the present Study was to determine the effects of voluntary wheel running on the PKB/mTOR signaling pathway in muscles front aged mice (20-22 months). The total levels of mTOR were 65% higher in gastrocnemius muscles from aged mice subjected to wheel running compared to aged sedentary mice (p=0.02)," scientists...
Source: Obesity & Diabetes Week (2004-05-31)
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