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Adiposity

Central obesity increases risk for elevated liver enzymes and disease

Published in Obesity and Diabetes Week, May 31st, 2004

Central obesity is an independent risk factor for elevated liver enzymes and liver disease.

"Regional body fat distribution may represent an independent risk factor for several conditions, especially metabolic and cardiovascular diseases; recent findings have shown that abdominal fat accumulation can be an independent predictor of hepatic steatosis.

"Very few studies, mostly using selected clinical samples, have focused on the relationship between indices of abdominal visceral fat accumulation and the most commonly used biochemical liver tests, such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and gamma-glutamyltransferase...

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