Endocrinology

Metabolic products measured by NMR analysis of one glucose derivative

Published in Obesity and Diabetes Week, June 21st, 2004

Scientists have measured glucose production, gluconeogenesis, and hepatic tricarboxylic acid cycle fluxes by nuclear magnetic resonance (NMR) analysis of a single glucose derivative.

According to recent research from the United States, "A triple-tracer method was developed to provide absolute fluxes contributing to endogenous glucose production and hepatic tricarboxylic acid (TCA) cycle fluxes in 24-hour-fasted rats by ²H and ¹³C nuclear magnetic resonance (NMR) analysis of a single glucose derivative.

"A primed, intravenous (3,4-¹³C₂ ) glucose infusion was used to measure endogenous glucose production;...

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Source: Obesity and Diabetes Week (2004-06-21)

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