Addiction Medicine
Liver function test results for naltrexone patients may be misleading
Published in Obesity and Diabetes Week, June 28th, 2004
"Many clinicians appear to be concerned about the potential hepatotoxicity of the opiate antagonist naltrexone (NTX) and this may be one reason why it is not used more widely in treating both heroin and alcohol abusers. Some much-quoted early studies noted abnormalities in liver function tests (LFTs) in very obese patients taking high doses, although there was no evidence of clinically significant liver dysfunction," researchers in England report.
"These concerns may be reinforced by advice in the U.K. product information sheet to perform LFTs before and during treatment, by high...
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