Exercise
Interleukin-6 deficient mice exhibit reduced exercise endurance
Published in Obesity and Diabetes Week, August 2nd, 2004
According to recent research from Sweden, "IL-6 is produced and released in large amounts from skeletal muscle during prolonged exercise in both mice and humans, but there are few data indicating the biological significance of this. IL-6 exerts metabolic effects such as stimulating energy expenditure and reducing body fat mass. We have now investigated the effects of IL-6 deficiency on exercise endurance and energy expenditure in pre-obese and obese IL-6-deficient (IL-6-/-) mice."
"Four-month-old pre-obese and 7-month-old obese IL-6-/- male mice backcrossed to...
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