Obesity Therapy
Food intake inhibited by oral oleoylethanolamide
Published in Obesity and Diabetes Week, August 2nd, 2004
"Oleoylethanolamide (OEA) may be an endogenous regulator of food intake, and intraperitoneal injection of this compound decreases food intake in 24-hour-starved rats. It is generally believed that this kind of lipid amide is rapidly catabolized in the gastrointestinal tract, thereby preventing its use as an oral anti-obesity compound," scientists in Denmark report.
"We now show that oral OEA inhibits food intake dose dependently at 90 minutes after food presentation to starved rats," said Mie Julin Nielsen and collaborators at the Danish University of Pharmaceutical Sciences and the Royal...
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