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Obesity & Diabetes

Normal and insulin-resistant models respond differently to linoleic acid

Published in Obesity and Diabetes Week, August 9th, 2004

Normal and insulin-resistant rodent models respond differently to dietary conjugated linoleic acid.

According to published research from Canada, "Dietary conjugated linoleic acid (CLA) is being investigated for beneficial effects for disease prevention and treatment in a variety of experimental models, including obesity and type 2 diabetes. To date, rodent studies suggest that trans-10,cis-12 (t10,02) CLA is associated with greater insulin resistance, despite lower body fat, and that a CLA mixture (and perhaps c9,t11) could be beneficial for the management of insulin resistance."

"Studies investigating the mechanisms by which CLA operates at the...

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