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Atherosclerosis

Circulating leptin associated with oxidized LDL in postmenopausal women

Published in Obesity and Diabetes Week, August 30th, 2004

Circulating leptin is associated with oxidized low density lipoprotein (LDL) in postmenopausal women, report researchers in Italy.

"Recently, leptin has been suggested as a possible cause of atherosclerotic disease. In the present study, we have investigated in postmenopausal women (n=60; age: 52 ± 13) the relationship between circulating levels of leptin, oxidized LDL (Ox-LDL), and other biochemical and anthropometric variables of atherosclerotic risk. In addition, we have evaluated soluble thrombomodulin (sTM) as a marker of endothelial damage," wrote E. Porreca and colleagues, University of Chieti.

According to their report, "Ox-LDL showed...

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