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Diabetes Pathogenesis
Prolactin-modulated gene expression profiles in pancreatic islets reported
September 27th, 2004
Researchers report prolactin-modulated gene expression profiles in pancreatic islets from adult female rats in a recent issue of Molecular and Cellular Endocrinology. According to a study from Brazil, "The effects of prolactin (PRL) on transcript profile expression in 24-hour cultured pancreatic adult rat islets were investigated by cDNA expression array analysis to identify possible candidate mRNA species that encode proteins involved in the maturation and growth of the endocrine pancreas. The expression of 54 out of 588 genes was altered by treatment with PRL. The differentially expressed transcripts identified were distributed in six main categories involved...
Source: Obesity & Diabetes Week (2004-09-27)
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