Obesity & Diabetes Week
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Insulin Delivery
Oral delivery of insulin accomplished using intestinal patches
September 27th, 2004
Scientists have developed a method for the oral delivery of insulin using intestinal patches. "Oral drug delivery, though attractive compared to injections, cannot be utilized for the administration of peptides and proteins due to poor epithelial permeability and proteolytic degradation within the gastrointestinal tract. A novel method is described that utilizes mucoadhesive intestinal patches to deliver therapeutic doses of insulin into systemic circulation. Intestinal patches localize insulin near the mucosa and protect it from proteolytic degradation," researchers in the United States report. "In vitro experiments confirmed the secure adhesion of...
Source: Obesity & Diabetes Week (2004-09-27)
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