Lipid Studies
Interleukin-15 directly regulates lipolysis in primary pig adipocytes
Published in Obesity and Diabetes Week, October 18th, 2004
"We recently provided evidence that interleukin-15 (IL-15) is expressed lowly in the pig adipocyte and that interferon-gamma (IFN-gamma) markedly increases this expression through a pathway regulated in part by protein kinase C. In the present study, we tested the hypothesis that IL-15 acts directly on the adipocyte to regulate lipid accretion by enhancing lipolysis or suppressing lipogenesis. Using recombinant porcine IL-15, we determined that this cytokine stimulates lipolysis in a dose-dependent manner (p<0.001)," scientists in the United States report.
"Furthermore,...
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