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Obstetrics

Marijuana use could cause tubal pregnancies, murine study suggests

Published in Obesity and Diabetes Week, October 18th, 2004

Marijuana use may increase the risk of ectopic (tubal) pregnancies, researchers at Vanderbilt University Medical Center say.

The researchers studied CB1, a cannabinoid receptor that binds the main active chemical for marijuana, delta-9-tetrahydrocannabinol (THC) .

In pregnant mice that lacked the gene for the receptor, or in which the receptor was blocked, the embryo failed to go through the oviduct - the tube leading from the ovaries to the uterus. The same thing happened in normal mice when the receptor was over-stimulated.

The study, published in the journal Nature Medicine, describes for the first time how the CB1...

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