Insulin Resistance
Growth hormone receptor gene disruption increases insulin sensitivity
Published in Obesity and Diabetes Week, November 1st, 2004
According to published research from Canada, "Growth hormone, acting through its receptor (GHR), plays an important role in carbohydrate metabolism and in promoting postnatal growth. GHR gene-deficient (GHR-/-) mice exhibit severe growth retardation and proportionate dwarfism. To assess the physiological relevance of growth hormone actions, GHR-/- mice were used to investigate their phenotype in glucose metabolism and pancreatic islet function."
"Adult GHR-/- mice exhibited significant...
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