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Obesity & Diabetes Week

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Diabetes Therapy



Bis(quercetinato)oxovanadium(IV) conjugate is insulin enhancing



December 6th, 2004

Scientists have synthesized a bis(quercetinato)oxovanadium(IV) conjugate with insulin-enhancing potential.

According to recent research published in the journal Bioorganic and Medicinal Chemistry Letters, " An oxovanadium complex of quercetin, exhibits highly potent insulin-enhancing activity in streptozotocin-induced diabetic mice."

"It also mimics mitogenic potential of insulin as evaluated by [3H]thymidine uptake assay making an effective, orally active insulin-enhancing agent for the treatment of both type 1 and type 2 diabetes without any noticeable toxic effects," stated Ruchi Shukla and colleagues at Pune University.

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Source: Obesity & Diabetes Week (2004-12-06)

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