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Obesity & Diabetes Week

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Diabetes Therapy



Insulin-releasing substance isolated from Gynostemma pentaphyllum



December 6th, 2004

Scientists have isolated a novel insulin-releasing substance, phanoside, from the plant Gynostemma pentaphyllum.

"Extracts from Gynostemma pentaphyllum Makino (Cucurbitaceae), a Southeast Asian herb, has been reported to affect numerous activities resulting in antitumor, cholesterol-lowering, immunopotentiating, antioxidant, and hypoglycemic effects. We have isolated one active compound by ethanol extraction, distribution in n-butyl alcohol/water, solid phase extraction/separation, and several rounds of reverse phase high pressure liquid chromatography," scientists in Sweden report.

"We have shown by NMR and mass spectrometry that this...


Source: Obesity & Diabetes Week (2004-12-06)

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