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Diabetic Nephropathy
ACE inhibitor/diuretic combination protects obese rat kidneys
December 6th, 2004
An angiotensin-converting enzyme (ACE) inhibitor/diuretic combination protected obese Zucker rat kidneys from fibrosis and renal failure. According to published research from France and Canada, "Some combinations of antihypertensive agents were shown to reduce proteinuria in patients with renal failure. However, preventive effects of such combinations on renal structure and function are presently unknown when treatment is administered before the onset of renal abnormalities. We thus investigated the long-term effects of an angiotensin-converting enzyme (ACE) inhibitor (perindopril)/diuretic (indapamide) combination (per/ind) in the Zucker rat, a classical model of...
Source: Obesity & Diabetes Week (2004-12-06)
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