Obesity & Diabetes Week
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Diabetic Neuropathy
Diabetic neuropathy accelerated in axons without neurofilaments
December 6th, 2004
Diabetic neuropathy is accelerated in axons without neurofilaments. According to a study from Canada, "Diabetic neuropathy is characterized by slowing of conduction velocity and axonal atrophy. Both of these cardinal features of neuropathy might be linked to impaired neurofilament investment of axons. Since neurofilaments form the critical structural latticework of axons, their importance in neuropathy is of interest. We tested directly the relationship of neurofilaments to diabetic neuropathy by superimposing streptozotocin-generated diabetes on a unique but viable transgenic mouse described by Eyer and Peterson." "These mice express a fusion...
Source: Obesity & Diabetes Week (2004-12-06)
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