Obesity & Diabetes Week
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Gestational Diabetes
No link found between gene polymorphism and GDM in a Taiwanese population
December 6th, 2004
Although the Trp64Arg polymorphism of beta(3)-adrenergic receptor (ADRB3) has been reported to be associated with insulin resistance and gestational diabetes mellitus (GDM), no such link was found in a group of pregnant Taiwanese women. P.J. Tsai of the Taipei Municipal Women's & Children's Hospital and colleagues recruited 299 pregnant women [(mean ± SD), 31.1 ± 4.2 years] for their study. "Two-hour, 75-g oral glucose tolerance tests (OGTT) were conducted at 24 to 31 weeks gestation (28.3 ± 1.6 weeks). Forty-one GDM subjects and 258 controls with normal glucose tolerance (NGT) level were genotyped for the ADRB3 Trp64Arg...
Source: Obesity & Diabetes Week (2004-12-06)
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