Obesity & Diabetes Week
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Leptin Studies
Leptin circadian phase difference in android and gynoid obesity found
December 6th, 2004
Scientists have discovered a circadian phase difference of leptin in android versus gynoid obesity. "A circadian rhythm in serum leptin, measured every four hours for 24 hours, characterizes normal-weight women (N=14), and women with gynoid (N=17) or android (N=26) obesity, peaking around midnight (p<0.05), but differing by about three hours between android and gynoid women (p<0.01)," investigators in France and the United States report. "Obesity is associated with a higher MESOR (rhythm-adjusted mean; p<0.001) and a smaller relative circadian amplitude (p<0.05)," reported Frederico Perfetto and collaborators at the University of Florence...
Source: Obesity & Diabetes Week (2004-12-06)
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