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Type 2 Diabetes

Pioglitazone shown to reverse thickening of carotid artery wall

Published in Obesity and Diabetes Week, December 6th, 2004

Clinical study results presented during the American Heart Association's Scientific Sessions 2004 proceedings have shown that the drug pioglitazone (ACTOS, Takeda) significantly reduced the thickness of the carotid (neck) artery in patients with type 2 diabetes.

By contrast, no change in carotid thickness was seen in a group of patients who received glimepiride, an older drug for type 2 diabetes.

"These results are provocative, because both drugs showed similar effects on lowering blood glucose, the traditional principal target for type 2 diabetes therapy," noted principal investigator Thomas Forst, professor for internal medicine, Institute for...

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