Liver Disease

Histological criteria guide the diagnosis of non-alcoholic steatohepatitis

Published in Obesity and Diabetes Week, December 13th, 2004

Histological criteria guide the diagnosis of non-alcoholic steatohepatitis.

"Thirty overweight patients with clinically characterized and biopsy proven non-alcoholic steatohepatitis (NASH) were enrolled in a 48-week treatment trial with rosiglitazone, a peroxisome proliferator-activator receptor (PPAR)-gamma agonist that enhances insulin sensitivity," said researchers in the United States.

"Improvement in laboratory liver tests, insulin resistance and liver fat content were documented; blinded biopsy review demonstrated decreases in necroinflammatory activity or grade and in individual components of grade, and changes in the relationship of lobular...

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Source: Obesity and Diabetes Week (2004-12-13)

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