Obesity Pathogenesis
Central administration of ghrelin preferentially enhances fat ingestion
Published in Obesity and Diabetes Week, December 13th, 2004
"Ghrelin, a brain-gut peptide discovered from the stomach, stimulates growth hormone release, food intake, adiposity, and weight gain. Circulating ghrelin levels are modulated under conditions of positive and negative energy balance, however its effect on macronutrient selection is not known. The present experiment investigates the effect of ghrelin on single and two-diet feeding paradigms in high-carbohydrate (HC) and high-fat (HF) preferring rats," scientists in Japan report.
"In the macronutrient selection test in which rats were given free access to either high-carbohydrate...
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