Obesity and Diabetes
IL-6 greater in preadipocytes than adipocytes of 3T3-L1 cells
Published in Obesity and Diabetes Week, December 20th, 2004
"Inflammation plays a major role in the development of chronic diseases such as cardiovascular disease and type 2 diabetes. Further, it was demonstrated that obese animals and humans have significantly higher levels of circulating proinflammatory cytokines, such as interleukin-6 (IL-6). The aim of this study was to determine whether adipose tissue could be a major source of circulating IL-6 in leptin-deficient obese (ob/ob) mice by comparing the expression of IL-6 in different tissues of ob/ob mice," researchers in the United States report.
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