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Atherosclerosis

Apolipoprotein linked to carotid thickness in diabetic patients

Published in Obesity and Diabetes Week, December 20th, 2004

Apolipoprotein C III levels are associated with carotid intima-media thickness in Chinese type 2 diabetic patients.

"Apolipoprotein C III (apo C III) plays a central role in regulating plasma metabolism of triglyceride-rich lipoprotein (TRL). The G3238C allele (Sst I) in the 3'-untranslated region has been found to be associated with raised apo C III levels and hypertriglyceridemia (HTG). Some Studies suggest that apo C III and the S2 allele of apo C III gene are independent risk factors for atherosclerotic diseases," scientists in China report.

"To study the potential association between these factors we analyzed the clinical data and...

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