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Obesity and Diabetes Week

Susan Hasty, Publisher

Table of Contents . . . December 27th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Obesity and Diabetes Week | Other Publications

Diabetes Pathogenesis - Insulin receptor substrate 2 plays key role in beta cells and hypothalamus

Diabetes Pathogenesis - Taurine increases glucose sensitivity of UCP2-overexpressing beta cells

Obesity and Diabetes - Dysregulation of insulin receptor substrate 2 causes obesity and diabetes

Obesity and Diabetes - Obesity-prone rats have defects in response to insulin-induced hypoglycemia

Obesity and Diabetes - Phospholipid fatty acid composition altered in obese type 2 diabetic patients

Adipogenesis - Notch pathway dispensable for adipocyte specification

Adverse Drug Effects - Rosiglitazone promotes osteoblast/osteocyte apoptosis

Allergies - First soy-based pediatric drink for children with milk allergies

Anorexia Nervosa - Cortisol secretory dynamics changes in anorexia affects bone metabolism

Atherosclerosis Pathogenesis - Diabetic mice resistant to prostaglandin D2 synthase effects

Beta-Adregenic Receptors - Normalizing the betaAR system prevents ventricular remodeling in heart failure

Business & Finance - Pharma company announces financial results

Childhood Obesity - Physicians' attitudes toward childhood obesity in Israel outlined

Cognition - DHEAS improves learning and memory in aged mice but not in diabetic mice

Collaborations - Medical technology company signs marketing, distribution agreement with Ivivi

Diabetes - FDA review period extension for chromium picolinate announced

Diabetes - PHER-O2 used to transport pancreas islet cells transplanted into humans

Diabetes Diagnosis - Potential beta-cell imaging agent synthesized

Diabetes Epidemiology - Prevalence of diabetes in Asian Indians living in U.S. reported

Diabetes Genomics and Genetics - IL-6 gene polymorphisms associated with type 2 diabetes

Diabetes Pathogenesis - High glucose potentiates cytokine-induced apoptosis of rat islet cells

Diabetes Pathogenesis - IRS2 takes center stage in development of type 2 diabetes

Diabetes Pathogenesis - Metabolic profile of hippocampus of Zucker diabetic fatty rats assessed

Diabetes Pathogenesis - Recent advances in CD38 autoimmunity are relevant to human diabetes

Diabetes Pathogenesis - Reduced Akt activity in beta cells induces defective insulin secretion

Diabetes Therapy - Action checklist of diabetes care measures presented

Diabetes Therapy - Acylated plus unacylated ghrelin strongly improves insulin sensitivity

Diabetes Therapy - Measuring gastric emptying time is useful in treating brittle diabetes

Diabetes Therapy - Metformin activates AMP-activated protein kinase

Diabetes Therapy - Metformin inhibits mitochondrial permeability transition and cell death

Diabetes Therapy - Natural compounds regulate activity of protein kinase C

Diabetes Therapy - Pioglitazone and sodium salicylate protect beta cells against apoptosis

Diabetes Therapy - Prostaglandin prevents alloxan cytotoxicity to insulinoma cells in vitro

Diabetes Treatment - Report: Endocrinologists, PCPs have different rationales driving choice of meds

Diabetic Cardiomyopathy - Natriuretic peptide useful for left ventricular abnormality screening

Diabetic Nephropathy - Aldosterone receptor antagonists prevent organ damage in diabetic patients

Diabetic Nephropathy - Overexpressed VEGF may nurture kidney disease in type II diabetics

Diabetic Nephropathy - Renal TGF-beta is dissociated from hypertrophy in female rats with diabetes

Diabetic Neuropathy - Acute effects of glycemic control on axonal excitability in diabetes reported

Diabetic Retinopathy - CML adduct over-stimulates angiogenesis in choroidal samples from diabetic rats

Diet and Nutrition - Effect of rice products on glucose and insulin in diabetic patients studied

Diet and Nutrition - Effects of high protein diets on thermogenesis, satiety and weight loss reviewed

Disease Management - Disease management company awarded four new accounts

Drug Development - Pharmaceutical firm reviews clinical pipeline

Eating Behavior - Night eating syndrome in obese persons not classified an eating disorder

Eating Behavior - Types of drink, but not food, can predict 6-year changes in waist circumference

Education - Pharma company announces diabetes scholarship for Native Americans

Erectile Dysfunction - Erectile dysfunction raises proinflammatory cytokines in obese men

Exercise & Nutrition - Diet-induced hyperphagia influenced by sex and exercise

Exercise and Health - Exercise alters phospholipid molecular species in rat skeletal muscle

Exercise and Health - Exercise training increases oxidative capacity in older adults

Eye Health - Biotech company announces discovery of treatment of ischemia-induced retinopathy

Finance - Gastrointestinal device company closes $16.9 million series B financing

Finance - Pharma company closes fourth round of private financing

Fitness & Wellness - BodyGem metabolism measurement devices selected for Equinox fitness program

Fitness & Wellness - Chocolatier says candy has health benefits; eat with caution experts advise

Fitness & Wellness - Hardee's hopes to have last laugh with Monster Thickburger

Fitness & Wellness - Online health improvement company partners with Wellspring Healthcare

Fitness & Wellness - USDA data show that peanuts can be Mother Nature's multivitamin

Food Safety - FDA releases study on presence of perchlorate in food and water supply

Geriatrics - Lowering hyperglycemia does not correct insulin secretion in older adults

Ghrelin Studies - Modified sham feeding decreases ghrelin levels in healthy humans

HIV/AIDS - Program offers HIV patients faster access to FUZEON

HIV/AIDS-Associated Lipodystrophy - Interleukin-18 linked to HIV-associated lipodystrophy

Hyperglycemia - Relaxation of rabbit artery is reduced by reactive oxygen species

Hypoglycemia - Hypoglycemic brain damage reviewed

Hyponatremia - U.S. FDA grants approval for investigational drug to treat hyponatremia

Insulin Delivery - Liposome formulations promote insulin penetration across Caco-2 monolayer

Insulin Resistance - Hexosamines play role in insulin resistance in adipose and muscle tissue

Insulin Resistance - Neutralization of TNF-alpha reverses insulin resistance in skeletal muscle

Insulin Sensitivity - Actions of PPAR-gamma agonism in absence of glucocorticoids investigated

Leptin Studies - Aged-obese rats respond to melanocortin agonist and antagonist

Leptin Studies - Food restriction and leptin impact brain reward circuitry in obese rats

Lovastatin - Lovastatin attenuates CD40-mediated inhibition of Abeta microglial phagocytosis

Metabolic Syndrome - Androgen effects on adipose tissue and metabolism in older men reported

Metabolic Syndrome - Metabolic syndrome linked to dysfunctional dense HDL particles

Metabolic Syndrome - UCONN, personalized medicine company, collaborate on obesity, metabolic syndrome

Morbid Obesity - Correcting saddlebag deformity in massive weight loss patient described

Nutrition - Milk vending machines flow into schools of Dairy Country

Nutrition - School nutrition group releases data on financial consequences of obesity

Obesity - Forecast: New drug could be safer for treating obesity than previous drugs

Obesity - Pharma company expands research scope to include obesity and diabetes

Obesity - Relationship between risk knowledge and obesity different for men and women

Obesity - Survey finds Americans believe obesity treatment should be included health plans

Obesity Genomics and Genetics - Two ancestral forms of neuromedin U-2 receptor gene reported

Obesity Pathogenesis - Cidea links brown adipose tissue and obesity

Obesity Pathogenesis - Hypothalamic melanin-concentrating hormone increased in obesity

Obesity Pathogenesis - Irregular patterns in daily weight chart at night predict weight regain

Obesity Pathogenesis - Macrophage migration inhibitory factor increased in obesity

Obesity Pathogenesis - Metabolically obese but normal-weight women characterized

Obesity Pathogenesis - SH2-B activates phosphatidylinositol 3-kinase in response to leptin

Obesity Risk Factor - Appetite regulation disturbed in women with polycystic ovary syndrome

Obesity Surgery - Computerized tomography safe after laparoscopic gastric bypass

Obesity Surgery - Robotic abdominal surgery reviewed

Obesity Surgery - Robotically assisted bariatric surgery reviewed

Obesity Therapy - Melanocortin-4 receptor activity plays role in energy homeostasis

Obesity and Diabetes - proopiomelanocortin gene polymorphism linked to insulin in obesity

Oral Mucositis - Company receives fast-track designation for CG53135

Pediatric Obesity - Teen struggles with the scale, self-image

Personnel - Managed care company adds health education coordinator

Personnel - Timothy W. Lawton, MD, named medical director of diabetes-focused company

Polycystic Ovary Syndrome - Metformin therapy benefits women with PCOS

Transplant Medicine - Research sets gestational window for harvesting porcine fetal pancreatic tissue

Weight Loss - Potential weight loss and vision benefits found in eggs

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