Diabetes Therapy
Prostaglandin prevents alloxan cytotoxicity to insulinoma cells in vitro
Published in Obesity and Diabetes Week, December 27th, 2004
According to a study from the United States, "In the present study, we studied the effect of various prostaglandins (PGs) on alloxan-induced cytotoxicity to rat insulinoma (RIN) cells. Of all the PGs tested, PGE1 , PGE2 , PGI2 , PGF1alpha , and PGF3alpha , protected RIN cells from alloxan-induced cytotoxicity (p<0.05 compared to alloxan), whereas thromboxane B2 and 6-keto-PGF1alpha were not effective. PGE1 induces a statistically significant increase in the activities of...
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