Published in Obesity and Diabetes Week, January 10th, 2005
"Clozapine is the gold standard treatment for Parkinson disease (PD) psychosis based on double-blinded, placebo-controlled trials, and has also been shown to alleviate tremor and dyskinesia. There is accumulating data suggesting that clozapine may be associated with increased frequency of diabetes mellitus (DM) compared to conventional neuroleptic drugs in treating schizophrenia. Forty-four predominantly geriatric parkinsonian subjects on clozapine for psychosis, tremor or dyskinesia, on an average dose of 50.6 mg/d for a mean duration of 41 months were reviewed,"...
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