Obesity Genomics and Genetics

Desnutrin is induced by fasting and glucocorticoids

Published in Obesity and Diabetes Week, January 10th, 2005

Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids.

According to a study from the United States, "We have used rat cDNA microarrays to identify adipocyte-specific genes that could play an important role in adipocyte differentiation or function. Here, we report the cloning and identification of a 2.0-kb mRNA coding for a putative protein that we have designated as desnutrin. The novel gene is expressed predominantly in adipose tissue, and its expression is induced early during 3T3-L1 adipocyte differentiation. Desnutrin mRNA levels were regulated by the nutritional status of animals, being...

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Source: Obesity and Diabetes Week (2005-01-10)

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