Published in Obesity and Diabetes Week, January 17th, 2005
According to recent research from the United States, "We investigated the effect of daily intracerebroventricular (ICV) leptin administration (neonatal age 2 to 7 days) on hypothalamic neuropeptides (neuropeptide Y, alpha-melanocyte-stimulating hormone) that regulate food intake, body weight (BW) gain, and the metabolic/hormonal profile in suckling (8 and 21 days) and adult rat (35, 60, 90, and 120 days). ICV leptin (0.16 mcg/g BW/dose; n=70) led to a postnatal decline in BW (p=0.0002) that persisted only in the adult females (p=0.002)."
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