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Metabolic Syndrome

Growth hormone and placental lactogen genes linked to metabolic syndrome

Published in Obesity and Diabetes Week, January 24th, 2005

A common polymorphism in the growth hormone and placental lactogen gene cluster is associated with development of the metabolic syndrome.

According to recent research from England, "Low rates of fetal and infant growth are associated with the metabolic syndrome and cardiovascular disease in later life. We investigated common genetic variation in the GH-CSH gene cluster on chromosome 17q23 encoding GH, placental lactogens [chorionic somatomammotropins (CSH)], and placental GH variant in relation to fetal and infant growth and phenotypic features of the metabolic syndrome in subjects aged 59-72 years from Hertfordshire, U.K. Allele groups T, D1, and D2 of a locus herein...

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