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Diabetes Pathogenesis

Findings describe new data in diabetes pathogenesis research

Published in Obesity and Diabetes Week, January 24th, 2005

Diabetes pathogenesis research advances have been reported from Japan, Denmark and the United States.

Study 1: Researchers outline the mechanism of caffeine inhibition on insulin-stimulated glucose uptake in adipose cells in a recent issue of Biochemical Pharmacology.

According to recent research from Japan, "Caffeine inhibits insulin-induced glucose uptake in rat adipocytes and also decreases insulin sensitivity, including whole-body glucose disposal and glucose uptake in skeletal muscle, during a euglycemic-hyperinsulinemic clamp in human. However, the mechanism by which caffeine decreases the insulin sensitivity is not still clear. We found...

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