Cardiology

Studies focused on cardiac function in Trypanosoma cruzi-infected mice

Published in Obesity and Diabetes Week, February 21st, 2005

A recent report describes studies of membrane fluidity and heart contractile force in Trypanosoma cruzi-infected mice.

According to recent research published in the journal Memorias Do Instituto Oswaldo Cruz, "In Chagas disease, serious cardiac dysfunction can appear. We specifically studied cardiac function by evaluating ventricle contractile force and norepinephrine response, affinity and density of beta-adrenergic receptors, dynamic properties of myocardial membranes, and electrocardiography. Albino Swiss mice (n=250) were infected with 55 trypomastigotes (Tulahuen strain) and studied at 35, 75, and 180 days post-infection, which correspond to the...

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Source: Obesity and Diabetes Week (2005-02-21)

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