Obesity Pathogenesis
Researchers publish new studies and findings in the area of obesity pathogenesis
Published in Obesity and Diabetes Week, March 7th, 2005
Study 1: Carbohydrate response element binding protein directly promotes lipogenic enzyme gene transcription.
According to recent research from the United States, "Carbohydrate response element (ChRE)-binding protein (ChREBP) is a recently discovered transcription factor that is activated in response to high glucose concentrations in liver independently of insulin. ChREBP was first identified by its ability to bind the ChRE of the liver pyruvate kinase (LPK) gene. We recently reported that the increase in expression of multiple liver lipogenic enzyme mRNAs...
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