Diabetes Pathogenesis
Impaired response to glucose load linked to low glucose storage
Published in Obesity and Diabetes Week, March 7th, 2005
According to a study from the Czech Republic, "The aim of the study was to determine the contribution of skeletal muscle, adipose tissue, and liver to the impaired glucose clearance manifesting itself during the initial phase of OGTT in a non-obese animal model of insulin resistance, hereditary hypertriglyceridemic (HHTg) rats. Glucose utilization and storage in insulin target tissues in vivo and in vitro after a glucose load (3 g/kg body weight) administered intragastrically following overnight fasting was compared in adult...
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