Diabetic Neuropathy

Neural redox stress in type 2 diabetes and neuropathy reviewed

Published in Obesity and Diabetes Week, March 7th, 2005

Neural redox stress and remodeling in metabolic syndrome, type 2 diabetes mellitus, and diabetic neuropathy.

"Diabetic polyneuropathy (DPN) is the most common complication of diabetes and may frequently be the presenting symptom in type 2 diabetes mellitus (T2DM). Metabolic syndrome and T2DM are associated with multiple metabolic toxicities. These substrate toxicities support the formation of reactive oxygen species (ROS), which are so damaging to cells, tissues and organs and play an important role in the development of multiple diabetic complications. The importance of redox stress (ROS) and their effect on the neuronal unit are discussed," researchers in the United...

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Source: Obesity and Diabetes Week (2005-03-07)

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