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Diet and Nutrition

Low-AGE content of low-fat vegan diets could benefit diabetic patients

Published in Obesity and Diabetes Week, March 21st, 2005

The low-AGE content of low-fat vegan diets could benefit diabetic patients, although concurrent taurine supplementation may be needed to minimize endogenous AGE production.

According to a study from the United States, "Increased endogenous generation of advanced glycation end products (AGEs) contributes importantly to the vascular complications of diabetes, in part owing to activation of the pro-inflammatory RAGE receptor. However, AGE-altered oligopeptides with RAGE-activating potential can also be absorbed from the diet, and indeed make a significant contribution to the plasma and tissue pool of AGEs; this contribution is especially prominent when compromised renal...

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