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Morbid Obesity

Adiposity plays role in obesity-related, low-grade inflammation

Published in Obesity and Diabetes Week, March 21st, 2005

Adiposity plays a role in obesity-related, low-grade inflammation.

"Metabolic alterations such as insulin resistance are thought to underlie the endothelial dysfunction and low grade inflammation found in morbid obesity. Twenty-six morbidly obese patients, aged 39.0±10.0 (mean±SD), were evaluated before and 4.2±0.8 months after bariatric surgery. A marked increment in the insulin sensitivity index (SI ) and the endothelium-dependent vasodilatory response in a dorsal hand vein was observed after weight loss following bariatric surgery," scientists in Spain report.

"Circulating levels of E-selectin, P-selectin,...

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