Obesity Genomics and Genetics
Prevalence of mutations of melanocortin 4 receptor variants reported
Published in Obesity and Diabetes Week, March 21st, 2005
According to published research from Denmark, "Mutations in the gene encoding the melanocortin 4 receptor (MC4R) are associated with the most common monogenic form of obesity. We examined 750 Danish men with juvenile-onset obesity (body mass index 33.3±2.4 kg/m2) and 706 control subjects (body mass index 21.4±2.1 kg/m2) for mutations in MC4R. A total of 14 different mutations were identified of which two, Ala219Val and Leu325Phe, were novel variants."
"The...
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