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Obesity

Therapeutic targets for obesity-associated diabetes based on inflammation link

Published in Obesity and Diabetes Week, March 28th, 2005

Therapeutic targets for obesity-associated diabetes may be based on a link to inflammation.

According to a published report from the United States, "The epidemic of obesity-associated diabetes is a major crisis in modern societies, in which food is plentiful and exercise is optional. The biological basis of this problem has been explored from evolutionary and mechanistic perspectives."

M.A. Lazar and coworkers of the University of Pennsylvania wrote, "Evolutionary theories, focusing on the potential survival advantages of 'thrifty' genes that are now maladaptive, are of great interest but are inherently speculative and difficult to prove."

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