Diabetes Therapy

Role of glucagon-like peptide 1 in treatment of diabetes reviewed

Published in Obesity and Diabetes Week, April 25th, 2005

Researchers review the role of glucagon-like peptide 1 in the treatment of diabetes in a recent issue of Hormone and Metabolic Research.

According to a study from Germany and the United States, "Glucagon-like peptide 1 (GLP-1) was discovered as an incretin (insulinotropic gut) hormone. Biological actions of GLP-1 in healthy and type 2 diabetic subjects include: stimulation of insulin secretion in a glucose-dependent manner; suppression of glucagon, reduction in appetite and food intake, and deceleration of gastric emptying. In animal experiments, in addition, stimulation of beta-cell neogenesis, growth and differentiation in animal and tissue culture experiments,...

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Source: Obesity and Diabetes Week (2005-04-25)

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