Published in Obesity and Diabetes Week, May 2nd, 2005
"In the general population, a high body mass index (BMI; in kg/m2) is associated with increased cardiovascular disease and all-cause mortality. However, the effect of overweight (BMI=25-30) or obesity (BMI>30) in patients with chronic kidney disease (CKD) undergoing maintenance hemodialysis (MHD) is paradoxically in the opposite direction; i.e., a high BMI is associated with improved survival. Although this 'reverse epidemiology' of obesity or dialysis-risk-paradox is relatively consistent in MHD patients, studies in CKD patients undergoing peritoneal dialysis have yielded mixed results,"...
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