Published in Obesity and Diabetes Week, May 9th, 2005
Study 1: Researchers have investigated beta-cell function in subjects spanning the range from normal glucose tolerance to overt diabetes.
According to a study from the United States and Italy, "The nature of the progressive beta-cell failure occurring as normal glucose tolerant (NGT) individuals progress to type 2 diabetes (T2DM) is incompletely understood. We measured insulin sensitivity (by a euglycemic insulin clamp) and insulin secretion rate (by deconvolution of plasma C-peptide levels during an oral glucose tolerance test) in 188 subjects [19 lean NGT...
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